Morphometric characteristics of distal airways of guinea pigs sensitized with ovalbumin

The Effect of Carvacrol on Serum Cytokines and Endothelin Levels of Ovalbumin Sensitized Guinea-Pigs

the effect of carvacrol on serum cytokines and endothelin levels of ovalbumin sensitized guinea-pigs

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Effect of thymoquinone on the lung pathology and cytokine levels of ovalbumin-sensitized guinea pigs.

Different pharmacological effects from Nigella sativa have been demonstrated in guinea pig tracheal chains in previous studies. In the present study, the prophylactic effects of thymoquinone on lung pathology as well as blood IL-4 and IFN-γ levels in sensitized guinea pigs were examined. Three groups of guinea pigs sensitized to ovalbumin were given drinking water alone (group S) or drinking wa...

The Effect of Carvacrol on Serum Cytokines and Endothelin Levels of Ovalbumin Sensitized Guinea-Pigs

OBJECTIVE(S) Different pharmacological effects of carvacrol including relaxant effect, its inhibitory effect on muscarinic and histamine (H1) and stimulatory effect on β-adrenoceptors have been demonstrated on guinea pig tracheal chains in previous studies. In the present study, the effect of carvacrol on blood IL-4, IFN- γ and endothelin levels of sensitized guinea pigs is examined. MATERIAL...

Influence of roflumilast on airway reactivity and apoptosis in ovalbumin-sensitized Guinea pigs.

Chronic inflammatory diseases, associated with airway obstruction and cough, are usually treated with bronchodilating and anti-inflammatory drugs. Inhibition of phosphodiesterases (PDE) leads to both of these effects and influences apoptosis of immune cells. In chronic obstructive pulmonary disease, roflumilast, a selective PDE4 inhibitor, has been recently approved for pharmacotherapy. The aim...